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CD16, Functional Grade, clone: B73.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-0167-85

Code : Z2

Additional Details : Weight : 0.00250kg

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Product Code. 15109354

  • £245.16 / 500Āµg


EU Stock 4
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Description

Description

Description: This B73.1 monoclonal antibody reacts with human CD16, a member of the Fc receptor family also known as Fc gamma RIIIa and Fc gamma RIIIb. This 50-65kDa receptor is expressed on natural killer cells, neutrophils, monocytes, and macrophages. Crosslinking of CD16 in natural killer cells and monocytes results in activation of the MAPK and PI3K signaling pathways, thus regulating the production of TNF alpha, IL-6, and IL-1 beta.This monoclonal antibody has been shown to block Fc receptor functions.Applications Reported: This B73.1 antibody has been reported for use in functional blocking assays and flow cytometric analysis.Applications Tested: This B73.1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

CD16
Monoclonal
1mg/mL
PBS with no preservative; pH 7.2
O75015, P08637
FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow CytometryĆ¾Functional Assay
B73.1
Functional Grade
FCGR3A
Purified
FCGR3A, FCGR3B
IgG1, kappa
500μg
Store at 2-8°C.
Primary
2214, 2215
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