CD16 Mouse anti-Human, Clone: B73.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0167-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.00250kg



Disclaimers: For Research Use Only.

Product Code. 15109354

Quantity Price
1 £ 237.85 / 500µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Format Purified
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Antigen CD16
Clone B73.1
Regulatory Status RUO
Isotype IgG1
Species Reactivity Human
Conjugate Unlabeled
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL
Primary or Secondary Primary
Quantity 500μg
Storage Requirements Store at 2-8°C.
Gene Alias Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR3

This B73.1 monoclonal antibody reacts with human CD16, a member of the Fc receptor family also known as Fc gamma RIIIa and Fc gamma RIIIb. This 50-65kDa receptor is expressed on natural killer cells, neutrophils, monocytes, and macrophages. Crosslinking of CD16 in natural killer cells and monocytes results in activation of the MAPK and PI3K signaling pathways, thus regulating the production of TNF alpha, IL-6, and IL-1 beta.

This monoclonal antibody has been shown to block Fc receptor functions.