CD16 Mouse anti-Human, Clone: B73.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0167-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208397

Quantity Price
1 £ 133.91 / 100µg
EU Stock 1
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Description and Specification

Specification

Isotype IgG1
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Formulation aqueous buffer, no sodium azide
Antigen CD16
Host Species Mouse
Format Purified
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Gene Alias Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR3
Concentration 1mg/mL
Primary or Secondary Primary
Quantity 100μg
Clone B73.1
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO

This B73.1 monoclonal antibody reacts with human CD16, a member of the Fc receptor family also known as Fc gamma RIIIa and Fc gamma RIIIb. This 50-65kDa receptor is expressed on natural killer cells, neutrophils, monocytes, and macrophages. Crosslinking of CD16 in natural killer cells and monocytes results in activation of the MAPK and PI3K signaling pathways, thus regulating the production of TNF alpha, IL-6, and IL-1 beta.

This monoclonal antibody has been shown to block Fc receptor functions.