CD158f Mouse anti-Human, PE-Cy7, Clone: HP-MA4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-1589-42

Product Code. 15578496

Disclaimers:

For Research Use Only.

Description

The monoclonal antibody HP-MA4 recognizes several CD158 proteins, also known as KIR2D, specifically KIR2DL1 (CD158a), KIR2DS1 (CD158h), KIR2DS3, and KIR2DS5 (CD158g). It does not recognize KIR2DL2 (CD158b1), KIR2DS2 (CD158j), KIR2DL4 (CD158d) or KIR2DS4 (CD158i) and crossreactivity to KIR2DL3 (CD158b2) and KIR2DL5 (CD158f) are unknown. CD158 proteins are members of the killer cell immunoglobulin-like receptors (KIR) family of transmembrane glycoproteins that are expressed on NK cells and a subset of T cells. Each KIR has an isoform with either a short (S) or long (L) cytoplasmic domain which transduces either an activating or inhibitory signal, respectively. The crossreactivity of the HP-MA4 antibody to KIR2DS3 and KIR2DS5 was published in 2013.

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Specifications

• Antigen: CD158f
• Clone: HP-MA4
• Conjugate: PE-Cy7
• Format: Conjugated
• Host Species: Murine
• Quantity: 100 Tests
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Concentration: 5μL (0.25μg)/test
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Gene Alias: KIR2DL1, KIR2DS1, KIR2DS3, KIR2DS5
• Isotype: IgG2b
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human