CD158f Mouse anti-Human, PE, Clone: UP-R1, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1588-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15576906

Quantity Price
1 £ 84.99 / 25 tests
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification


Species Reactivity Human
Applications Flow Cytometry
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test
Isotype IgG1
Host Species Mouse
Clone UP-R1
Antigen CD158f
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate PE
Gene Alias KIR2DL5/S5, KIR
Monoclonal or Polyclonal Monoclonal
Quantity 25 tests
Regulatory Status RUO
Format Conjugated

This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain.

The UP-R1 antibody has been shown to inhibit NK cytotoxicity.