CD158f Mouse anti-Human, PE, Clone: HP-MA4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1589-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15596906

Quantity Price
1 £ 60.53 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Gene Alias KIR2DL1, KIR2DS1, KIR2DS3, KIR2DS5
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Clone HP-MA4
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD158f
Regulatory Status RUO
Host Species Mouse
Primary or Secondary Primary
Format Conjugated
Quantity 25 tests
Isotype IgG2b
Applications Flow Cytometry
Species Reactivity Human
Concentration 5μL (0.25μg)/test
Conjugate PE

The monoclonal antibody HP-MA4 recognizes several CD158 proteins, also known as KIR2D, specifically KIR2DL1 (CD158a), KIR2DS1 (CD158h), KIR2DS3, and KIR2DS5 (CD158g). It does not recognize KIR2DL2 (CD158b1), KIR2DS2 (CD158j), KIR2DL4 (CD158d) or KIR2DS4 (CD158i) and crossreactivity to KIR2DL3 (CD158b2) and KIR2DL5 (CD158f) are unknown. CD158 proteins are members of the killer cell immunoglobulin-like receptors (KIR) family of transmembrane glycoproteins that are expressed on NK cells and a subset of T cells. Each KIR has an isoform with either a short (S) or long (L) cytoplasmic domain which transduces either an activating or inhibitory signal, respectively. The crossreactivity of the HP-MA4 antibody to KIR2DS3 and KIR2DS5 was published in 2013.