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CD158f Monoclonal Antibody (UP-R1), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£133.00 - £265.00

Specifications

Antigen CD158f
Clone UP-R1
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15528026
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Affymetrix eBioscience
17-1588-41
25 Tests
£133.00
25 tests
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Estimated Shipment: 25-04-2024
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15538026
View Documents Promotion Details
Affymetrix eBioscience
17-1588-42
100 Tests
£265.00
100 tests
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Estimated Shipment: 25-04-2024
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Description

Description

Description: This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain. The UP-R1 antibody has been shown to inhibit NK cytotoxicity. Applications Reported: This UP-R1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This UP-R1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD158f Monoclonal antibody specifically detects CD158f in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD158f
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
CD158; CD158F; CD158f1; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A; killer cell immunoglobulin-like receptor 2DL5A; killer cell immunoglobulin-like receptor KIR2DL5A; killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A; killer-cell Ig-like receptor; KIR2DL; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; NKAT; NKAT1
KIR2DL5A
Primary
4° C, store in dark, DO NOT FREEZE!
KIR2DL5A
UP-R1
Flow Cytometry
APC
Mouse
Human
Q8N109
57292
IgG1
Affinity chromatography
Antibody
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