CD158a/h/g Mouse anti-Human, APC, Clone: HP-MA4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1589-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15558026

Quantity Price
1 £ 152.25 / 100 tests
EU Stock 2
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Description and Specification

Specification

Primary or Secondary Primary
Clone HP-MA4
Regulatory Status RUO
Antigen CD158a/h/g
Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Host Species Mouse
Concentration 5μL (0.125μg)/test
Format Conjugated
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate APC
Gene Alias KIR2DL1, KIR2DS1, KIR2DS3, KIR2DS5
Isotype IgG2b

The monoclonal antibody HP-MA4 recognizes several CD158 proteins, also known as KIR2D, specifically KIR2DL1 (CD158a), KIR2DS1 (CD158h), KIR2DS3, and KIR2DS5 (CD158g). It does not recognize KIR2DL2 (CD158b1), KIR2DS2 (CD158j), KIR2DL4 (CD158d) or KIR2DS4 (CD158i) and crossreactivity to KIR2DL3 (CD158b2) and KIR2DL5 (CD158f) are unknown. CD158 proteins are members of the killer cell immunoglobulin-like receptors (KIR) family of transmembrane glycoproteins that are expressed on NK cells and a subset of T cells. Each KIR has an isoform with either a short (S) or long (L) cytoplasmic domain which transduces either an activating or inhibitory signal, respectively. The crossreactivity of the HP-MA4 antibody to KIR2DS3 and KIR2DS5 was published in 2013.