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CD157, APC, clone: eBioSY11B5 (SY11B5), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1579-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15518026

  • £183.54 / 100 tests


EU Stock 5
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Description

Description

Description: The eBioSY11B5 monoclonal antibody recognizes human CD157 (Mo5, BST-1). CD157 is a 42-45 kDa, GPI-anchored protein with structural and functional similarities with CD38. CD157 was initially cloned because of its expression on monocytes and macrophages, and was subsequently discovered to be the same protein named BST-1, discovered for its expression on bone marrow stromal cells and its ability to stimulate the proliferation of a mouse pre-B cell line. CD157 is a pleiotropic ectoenzyme and is thought to act independently as an enzyme and receptor. Similar to CD38, CD157 is involved in the metabolism of NAD+ and this activity may be involved in regulating intracellular Ca2+ levels. As a receptor, upon binding of its putative ligand, CD157 is thought to initiate a signal transduction cascade resulting in the phosphorylation of cytoplasmic proteins including focal adhesion kinase (FAK). The mechanism and functional significance of CD157-initiated signal transduction remain to be fully characterized.Applications Reported: This eBioSY11B5 (SY11B5) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioSY11B5 (SY11B5) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD157
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q10588
Bone marrow stromal cell antigen 1, ADP-ribosyl cyclase 2, BST-1, NAD+ nucleosidase, bone marrow stromal antigen 1, cADPr hydrolase 2, cyclic ADP-ribose hydrolase 2
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioSY11B5 (SY11B5)
APC
BST1
Conjugated
BST1
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
683
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