missing translation for 'onlineSavingsMsg'
Learn More

CD154 (CD40 Ligand), clone: 24-31, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1548-82

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15277257

  • £124.85 / 100µg


EU Stock 2
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

Description: The 24-31 monoclonal antibody reacts with human CD154, a 39kDa transmembrane glycoprotein also known as gp39 and CD40 ligand (CD40L). CD154 is a member of the TNF superfamily and is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, CD154 serves a crucial function in T-APC cognate interaction. CD154 interaction with CD40 transduces signals for T-dependent B-cell activation and induces B cell cycle entry. 24-31 cross-reacts with the cynomolgus monkey CD154.Applications Reported: 24-31 has been reported for use in flow cytometric analysis. 24-31 has also been reported to block CD154 binding to CD40 and inhibit T cell-dependent B cell differentiation and antibody response in vitro . (Please use Functional Grade Purified 24-31, cat. 16-1548, in functional assays.).Applications Tested: The 24-31 antibody has been tested by flow cytometric analysis of resting and activated human normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD154 (CD40 Ligand)
24-31
Unconjugated
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal
Functional Assay
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CD40L
IgG1
RUO
Primary
Human
Videos