CD154 (CD40 Ligand) Mouse anti-Human, APC-eFluor 780, Clone: 24-31, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-1548-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15509576

Quantity Price
1 £ 182.82 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Host Species Mouse
Concentration 5μL (0.125μg)/test
Antigen CD154 (CD40 Ligand)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias CD40L
Primary or Secondary Primary
Regulatory Status RUO
Conjugate APC-eFluor 780
Format Conjugated
Species Reactivity Cynomolgus, Human
Clone 24-31
Applications Flow Cytometry

The 24-31 monoclonal antibody reacts with human CD154, a 39kDa transmembrane glycoprotein also known as gp39 and CD40 ligand (CD40L). CD154 is a member of the TNF superfamily and is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, CD154 serves a crucial function in T-APC cognate interaction. CD154 interaction with CD40 transduces signals for T-dependent B-cell activation and induces B cell cycle entry. 24-31 cross-reacts with the Cynomolgus monkey CD154.