CD154 (CD40 Ligand) Mouse anti-Human, APC-eFluor 780, Clone: 24-31, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-1548-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599566

Quantity Price
1 £ 97.22 / 25 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Antigen CD154 (CD40 Ligand)
Clone 24-31
Isotype IgG1
Format Conjugated
Gene Alias CD40L
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Conjugate APC-eFluor 780
Host Species Mouse
Quantity 25 tests
Primary or Secondary Primary
Species Reactivity Cynomolgus, Human
Applications Flow Cytometry
Concentration 5μL (0.125μg)/test

The 24-31 monoclonal antibody reacts with human CD154, a 39kDa transmembrane glycoprotein also known as gp39 and CD40 ligand (CD40L). CD154 is a member of the TNF superfamily and is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, CD154 serves a crucial function in T-APC cognate interaction. CD154 interaction with CD40 transduces signals for T-dependent B-cell activation and induces B cell cycle entry. 24-31 cross-reacts with the Cynomolgus monkey CD154.