CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, PerCP-eFluor 710, Clone: MR1, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-1541-80

25UG ANTI-MOUSE CD154 (CD40L) PERCP-EF710

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15351290

Quantity Price
1 £ 97.0 / 25µg
Estimated Shipment date
from Supplier 20-02-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD154 (CD40 Ligand)
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias CD40L
Host Species Armenian Hamster
Applications Flow Cytometry
Isotype IgG
Quantity 25μg
Regulatory Status RUO
Species Reactivity Mouse
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone MR1
Concentration 0.2mg/mL
Conjugate PerCP-eFluor 710

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.