CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, PE, Clone: MR1, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1541-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15208699

Quantity Price
1 £ 60.53 / 50µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Gene Alias CD40L
Isotype IgG
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 50μg
Conjugate PE
Format Conjugated
Antigen CD154 (CD40 Ligand)
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone MR1
Concentration 0.2mg/mL
Species Reactivity Mouse
Primary or Secondary Primary
Applications Flow Cytometry

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.