CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, PE, Clone: MR1, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1541-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15218699

Quantity Price
1 £ 121.67 / 100µg
EU Stock 4
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Description and Specification

Specification

Isotype IgG
Format Conjugated
Concentration 0.2mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Clone MR1
Antigen CD154 (CD40 Ligand)
Conjugate PE
Host Species Armenian Hamster
Primary or Secondary Primary
Gene Alias CD40L
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100μg
Species Reactivity Mouse

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.