CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, eFluor 450, Clone: MR1, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1541-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15539726

Quantity Price
1 £ 60.53 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Isotype IgG
Concentration 0.2mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Primary or Secondary Primary
Gene Alias CD40L
Regulatory Status RUO
Clone MR1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Species Reactivity Mouse
Conjugate eFluor 450
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Antigen CD154 (CD40 Ligand)

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.