CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, eFluor 450, Clone: MR1, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1541-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15549726

Quantity Price
1 £ 146.13 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Conjugate eFluor 450
Gene Alias CD40L
Species Reactivity Mouse
Quantity 100μg
Clone MR1
Isotype IgG
Concentration 0.2mg/mL
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Antigen CD154 (CD40 Ligand)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Format Conjugated
Host Species Armenian Hamster

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.