CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, Clone: MR1, Functional Grade, eBioscience™
Armenian Hamster Monoclonal Antibody, Functional Grade
Brand: Affymetrix eBioscience 16-1541-85
UNSPSC : 12352200
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionThe MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.
For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.
|CD154 (CD40 Ligand)|
|aqueous buffer, no sodium azide|
|Store at 2-8°C.|