CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, Clone: MR1, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1541-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15258577

Quantity Price
1 £ 182.82 / 500µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Concentration 1mg/mL
Isotype IgG
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Applications Flow Cytometry
Applications Functional Assay
Clone MR1
Antigen CD154 (CD40 Ligand)
Storage Requirements Store at 2-8°C.
Quantity 500μg
Format Purified
Conjugate Unlabeled
Species Reactivity Mouse
Formulation aqueous buffer, no sodium azide
Gene Alias CD40L
Primary or Secondary Primary

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.