CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, Clone: MR1, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1541-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15248577

Quantity Price
1 £ 91.11 / 100µg
EU Stock 1
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Description and Specification

Specification

Isotype IgG
Quantity 100μg
Applications Flow Cytometry
Applications Functional Assay
Antigen CD154 (CD40 Ligand)
Conjugate Unlabeled
Host Species Armenian Hamster
Gene Alias CD40L
Monoclonal or Polyclonal Monoclonal
Clone MR1
Concentration 1mg/mL
Format Purified
Formulation aqueous buffer, no sodium azide
Primary or Secondary Primary
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Regulatory Status RUO

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.