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CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, Clone: MR1, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-1541-81

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15238577

  • £48.31 / 50µg


Estimated Shipment
01-12-2017
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Disclaimers:

For Research Use Only.


Description

Description

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.
Specifications

Specifications

CD154 (CD40 Ligand)
MR1
Unconjugated
Purified
Armenian Hamster
50μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
CD40L
IgG
RUO
Primary
Murine