CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, Biotin, Clone: MR1, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-1541-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15249749

Quantity Price
1 £ 164.47 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Host Species Armenian Hamster
Applications Flow Cytometry
Format Conjugated
Quantity 500μg
Primary or Secondary Primary
Clone MR1
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG
Regulatory Status RUO
Species Reactivity Mouse
Gene Alias CD40L
Antigen CD154 (CD40 Ligand)
Concentration 0.5mg/mL
Conjugate Biotin

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.