missing translation for 'onlineSavingsMsg'
Learn More

CD151, APC, clone: 50-6, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1519-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15568016

  • £88.05 / 25 tests

Estimated Shipment date
from Supplier 25-04-2018
Add to basket



Description: The monoclonal antibody 50-6 recognizes human CD151 also known as PETA-3 (platelet-endothelial cell tetraspan antigen-3). CD151 has a molecular weight of 29kDa and like other tetraspanin family members, CD151 contains four hydrophobic transmembrane domains, two short cytoplasmic tails, and one small and one large extracellular loop. CD151 is expressed on platelets, megakaryocytes, endothelial cells, at the cell-cell junctions, as well as epithelial cells where it localizes to basolateral surfaces exposed to extracellular matrix. The tetraspanins play a role in cell adhesion and migration; CD151 interacts with integrinalpha3 beta1 and integrinalpha6 beta4. In particular CD151 forms a functional complex with c-Met and integrin alpha3 and alpha6 in human salivary gland cancer cells. Additionally it can interact with CD46. Together these interactions are thought to play a role during early metastasis as a potential positive effector. The 50-6 monoclonal antibody inhibits in vivo metastasis of a human epidermal carcinoma cell line, HEp-3.Applications Reported: This 50-6 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 50-6 antibody has been pre-titrated and tested by flow cytometric analysis of human platelets. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.


25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IgG1, kappa

For Research Use Only.