CD150 Rat anti-Mouse, FITC, Clone: mShad150, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-1502-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15228189

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Format Conjugated
Clone mShad150
Quantity 25μg
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Antigen CD150
Gene Alias SLAM, Signaling lymphocyte activation molecule
Regulatory Status RUO
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Conjugate FITC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL
Species Reactivity Mouse
Isotype IgG2b

The mShad150 monoclonal antibody reacts with mouse CD150, an ∽70kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T cells, in particular Th1, and B cells; this expression is rapidly upregulated upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. The mShad150 antibody has been reported to also stain the CD150+CD244-CD48-CD41- population of pluripotent hematopoietic stem cells.