CD150 Rat anti-Mouse, eFluor 450, Clone: mShad150, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1502-82

100UG Anti-Mouse CD150 eFluor 450

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15529726

Quantity Price
1 £ 287.9 / 100µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen CD150
Applications Flow Cytometry
Clone mShad150
Concentration 0.2mg/mL
Conjugate eFluor 450
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias SLAM, Signaling lymphocyte activation molecule
Host Species Rat
Isotype IgG2b
Quantity 100μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The mShad150 monoclonal antibody reacts with mouse CD150, an ∽70kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T cells, in particular Th1, and B cells; this expression is rapidly upregulated upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. The mShad150 antibody has been reported to also stain the CD150+CD244-CD48-CD41- population of pluripotent hematopoietic stem cells.