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CD150 Mouse anti-Human, PE, Clone: A12 (7D4), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1509-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15586896

  • £153.00 / 100 tests

Estimated Shipment date
from Supplier 30-03-2020

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Description

Description

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).
Specifications

Specifications

CD150
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q13291
CD150, CDw150, SLAM, IPO-3, signaling lymphocytic activation molecule, SLAMF1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
A12 (7D4)
PE
SLAMF1
Liquid
SLAMF1
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
6504
Videos
Documents

For Research Use Only.