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CD146 Mouse, PE, Clone: P1H12, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1469-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15536896

  • £61.11 / 25 tests


EU Stock 2
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody P1H12 recognizes CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50% of the mass from carbohydrates.

The antibody P1H12 has been reported to crossreact to mouse, rabbit, canine, but not rat.
Description & Specifications

Specifications

CD146
P1H12
PE
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
Conjugated
Melanoma Cell Adhesion Molecule, MUC18, Mel-CAM, EndoCAM
IgG1
RUO
Primary
Rabbit