CD146 Mouse, eFluor 660, Clone: P1H12, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-1469-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15549906

Quantity Price
1 £ 174.09 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Isotype IgG1
Concentration 5μL (0.06μg)/test
Conjugate eFluor 660
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100 tests
Species Reactivity Canine, Human, Mouse, Rabbit
Gene Alias Melanoma Cell Adhesion Molecule, MUC18, Mel-CAM, EndoCAM
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Antigen CD146
Host Species Mouse
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone P1H12
Applications Flow Cytometry

The monoclonal antibody P1H12 recognizes CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50% of the mass from carbohydrates.

The antibody P1H12 has been reported to crossreact to mouse, rabbit, canine, but not rat.