CD144 (VE-Cadherin) Rat anti-Mouse, PE, Clone: eBioBV13 (BV13), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1441-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15238679

Quantity Price
1 £ 192.42000000000002 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Gene Alias Cdh5, Cadherin 5, Vascular endothelial cadherin
Applications Flow Cytometry
Primary or Secondary Primary
Concentration 0.2mg/mL
Clone eBioBV13 (BV13)
Isotype IgG1
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate PE
Regulatory Status RUO
Host Species Rat
Antigen CD144 (VE-Cadherin)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100μg
Format Conjugated
Monoclonal or Polyclonal Monoclonal

The eBioBV13 (BV13) monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.