CD144 (VE-Cadherin) Rat anti-Mouse, eFluor 450, Clone: eBioBV13 (BV13), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1441-82

100UG ANTI-MOUSE CD144 (VE-CADHERIN) EF 450

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15391750

Quantity Price
1 £ 170.59 / 100µg
Estimated Shipment date
from Supplier 27-02-2017
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Description and Specification

Specification

Antigen CD144 (VE-Cadherin)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Cdh5, Cadherin-5, Vascular endothelial cadherin
Applications Flow Cytometry
Quantity 100μg
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone eBioBV13 (BV13)
Format Conjugated
Host Species Rat
Isotype IgG1
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Conjugate eFluor 450

The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.