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CD144 (VE-Cadherin) Rat anti-Mouse, Clone: eBioBV13 (BV13), Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-1441-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15208567

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Specifications

Description

The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.
Description & Specifications

Specifications

CD144 (VE-Cadherin)
eBioBV13 (BV13)
Unlabeled
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Western Blot
1mg/mL
aqueous buffer, no sodium azide
Cdh5, Cadherin-5, Vascular endothelial cadherin
IgG1
RUO
Primary
Murine