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CD144 (VE-Cadherin) Rat anti-Mouse, Clone: eBioBV13 (BV13), Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-1441-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15298557

  • £60.53 / 50µg


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Disclaimers:

For Research Use Only.


Description

Description

The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.
Specifications

Specifications

CD144
eBioBV13 (BV13)
Unconjugated
Purified
Rat
50μg
Store at 2-8°C.
Monoclonal
Western Blot
1mg/mL
aqueous buffer, no sodium azide
Cdh5, Cadherin-5, Vascular endothelial cadherin
IgG1
RUO
Primary
Murine