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CD144 (VE-cadherin), Alexa Fluor 488, clone: eBioBV13 (BV13), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-1441-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15352010

  • £229.96 / 100µg


Estimated Shipment date
from Supplier 27-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.Applications Reported: This eBioBV13 (BV13) antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections.Applications Tested: This eBioBV13 (BV13) antibody has been tested by flow cytometric analysis of bEnd.3 cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD144
eBioBV13 (BV13)
Alexa Fluor 488
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry (Frozen)
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Cdh5, Cadherin-5, Vascular endothelial cadherin
IgG1
RUO
Primary
Murine
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