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CD142 Mouse anti-Human, Clone: HTF-1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-1429-85

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15517786

  • £213.39 / 500µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa.

The HTF-1 antibody has been reported to exhibit blocking activity.
Specifications

Specifications

CD142
HTF-1
Unconjugated
Purified
Murine
500μg
Store at 2-8°C.
Monoclonal
Western Blot
1mg/mL
aqueous buffer, no sodium azide
Tissue Factor
IgG1
RUO
Primary
Human
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