CD142 Mouse anti-Human, Clone: HTF-1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1429-82

100UG Anti-Human CD142 Functional Grade Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15507786

Quantity Price
1 £ 129.5 / 100µg
Estimated Shipment date
from Supplier 09-12-2016
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Description and Specification

Specification

Antigen CD142
Applications Flow Cytometry
Applications Functional Assay
Applications Immunocytochemistry
Applications Western Blotting
Clone HTF-1
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias Tissue Factor
Host Species Mouse
Isotype IgG1
Quantity 100μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa.

The HTF-1 antibody has been reported to exhibit blocking activity.