CD142 Mouse anti-Human, Clone: HTF-1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1429-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15507786

Quantity Price
1 £ 84.99 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Species Reactivity Human
Clone HTF-1
Isotype IgG1
Applications Flow Cytometry
Applications Functional Assay
Applications Immunocytochemistry
Applications Western Blotting
Quantity 100μg
Antigen CD142
Regulatory Status RUO
Format Purified
Storage Requirements Store at 2-8°C.
Concentration 1mg/mL
Primary or Secondary Primary
Conjugate Unlabeled
Formulation aqueous buffer, no sodium azide
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Gene Alias Tissue Factor

This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa.

The HTF-1 antibody has been reported to exhibit blocking activity.