CD140b (PDGF Receptor b) Rat anti-Mouse, Clone: APB5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1402-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15247227

Quantity Price
1 £ 29.97 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Antigen CD140b (PDGF Receptor b)
Isotype IgG2a
Format Purified
Primary or Secondary Primary
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Host Species Rat
Conjugate Unlabeled
Clone APB5
Species Reactivity Mouse
Quantity 50μg
Gene Alias PDGFRbeta, PDGFR-beta, PDGFR beta, PDGFR b, PDGFR-b

The APB5 monoclonal antibody reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR beta chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.