CD140b (PDGF Receptor b) Rat anti-Mouse, Biotin, Clone: APB5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-1402-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15269729

Quantity Price
1 £ 111.78 / 100µg
EU Stock 2
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Description and Specification

Specification

Applications Flow Cytometry
Regulatory Status RUO
Format Conjugated
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Biotin
Antigen CD140b (PDGF Receptor b)
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Clone APB5
Isotype IgG2a
Gene Alias PDGFRbeta, PDGFR-beta, PDGFR beta, PDGFR b, PDGFR-b
Host Species Rat
Quantity 100μg
Storage Requirements Store at 2-8°C. Do not freeze.
Concentration 0.5mg/mL

The APB5 monoclonal antibody reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR beta chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.