CD14 Rat anti-Mouse, PE-Cy7, Clone: Sa2-8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0141-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15310900

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Format Conjugated
Isotype IgG2a
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Applications Flow Cytometry
Antigen CD14
Monoclonal or Polyclonal Monoclonal
Clone Sa2-8
Host Species Rat
Quantity 25μg
Primary or Secondary Primary
Concentration 0.2mg/mL
Conjugate PE-Cy7
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation).