CD14 Rat anti-Mouse, PE, Clone: Sa2-8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0141-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15278459

Quantity Price
1 £ 66.65 / 50µg
EU Stock 1
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Quantity 50μg
Antigen CD14
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2a
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Host Species Rat
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone Sa2-8
Concentration 0.2mg/mL
Primary or Secondary Primary

The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation).