CD14 Rat anti-Mouse, PE, Clone: Sa2-8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0141-83

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15298459

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Description and Specification

Specification

Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Applications Flow Cytometry
Isotype IgG2a
Concentration 0.2mg/mL
Antigen CD14
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone Sa2-8
Quantity 200μg
Conjugate PE
Regulatory Status RUO
Primary or Secondary Primary
Format Conjugated

The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation).