CD14 Rat anti-Mouse, Biotin, Clone: Sa2-8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0141-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15269459

Quantity Price
1 £ 91.11 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Isotype IgG2a
Clone Sa2-8
Regulatory Status RUO
Host Species Rat
Concentration 0.5mg/mL
Conjugate Biotin
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Quantity 100μg
Format Conjugated
Antigen CD14

The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation).