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CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), PE-Cyanine7, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£342.00

Specifications

Antigen CD137 (4-1BB)
Clone 4B4 (4B4-1)
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15805373
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Affymetrix eBioscience
25-1379-42
100 Tests
£342.00
Pack of 100
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Description

Description

Description: This 4B4 (4B4-1) monoclonal antibody reacts with human CD137 (also known as 4-1BB or TNFRSF9), which is an inducible member of the TNFR family of costimulatory molecules expressed on T cells, natural killer cells, dendritic cells, granulocytes, and mast cells. Involved in recruiting TNFR-associated factors (TRAF) 1 and 2, CD137 signaling plays a role in T cell activation, maintaining the survival of activated and CD8 memory T cells, as well as suppressing myelopoiesis and dendritic cell development. Stimulation of this receptor has also been shown to promote expansion of CD4+CD25+ T regulatory cells i{ex vivoi}. The ligand for CD137, 4-1BBL, is found on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. Applications Reported: This 4B4 (4B4-1) antibody has been reported for use in flow cytometric analysis. Applications Tested: This 4B4 (4B4-1) antibody has been tested by flow cytometric analysis on two-day Con A-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation.

CD137 (4-1BB) Monoclonal antibody specifically detects CD137 (4-1BB) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD137 (4-1BB)
5 μL/Test
Monoclonal
Liquid
RUO
Q07011
TNFRSF9
Primary
4° C, store in dark, DO NOT FREEZE!
TNFRSF9
4B4 (4B4-1)
Flow Cytometry
PE-Cyanine7
Mouse
Human
3604
IgG1 κ
Affinity chromatography
Antibody
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