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CD137 (4-1BB) Mouse anti-Human, PerCP-eFluor 710, Clone: 4B4 (4B4-1), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-1379-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15589186

  • £83.43 / 25 tests


Estimated Shipment date
from Supplier 04-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 4B4 (4B4-1) monoclonal antibody reacts with human CD137 (also known as 4-1BB or TNFRSF9), which is an inducible member of the TNFR family of costimulatory molecules expressed on T cells, natural killer cells, dendritic cells, granulocytes, and mast cells. Involved in recruiting TNFR-associated factors (TRAF) 1 and 2, CD137 signaling plays a role in T cell activation, maintaining the survival of activated and CD8 memory T cells, as well as suppressing myelopoiesis and dendritic cell development. Stimulation of this receptor has also been shown to promote expansion of CD4+CD25+ T regulatory cells \i{ex vivo\i}. The ligand for CD137, 4-1BBL, is found on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
Description & Specifications

Specifications

CD137 (4-1BB)
4B4 (4B4-1)
PerCP-eFluor 710
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
Conjugated
Ly-63, TNFRSF9, ILA
IgG1
RUO
Primary
Human