CD137 (4-1BB) Golden Syrian Hamster anti-Mouse, PerCP-eFluor 710, Clone: 17B5, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-1371-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15579186

Quantity Price
1 £ 180.16 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
Add to basket


Description and Specification

Specification

Conjugate PerCP-eFluor 710
Antigen CD137 (4-1BB)
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Clone 17B5
Quantity 100μg
Isotype IgG
Primary or Secondary Primary
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Golden Syrian Hamster
Gene Alias Ly-63, TNFRSF9, ILA
Applications Flow Cytometry
Regulatory Status RUO
Format Conjugated

The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays.