CD137 (4-1BB) Golden Syrian Hamster anti-Mouse, PE, Clone: 17B5, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1371-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15288669

Quantity Price
1 £ 117.31 / 100µg
EU Stock 4
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD137 (4-1BB)
Species Reactivity Mouse
Clone 17B5
Conjugate PE
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Gene Alias Ly-63, TNFRSF9, ILA
Host Species Golden Syrian Hamster
Isotype IgG
Primary or Secondary Primary
Concentration 0.2mg/mL
Quantity 100μg
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays.