CD137 (4-1BB) Golden Syrian Hamster anti-Mouse, eFluor 450, Clone: 17B5, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1371-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15579716

Quantity Price
1 £ 61.11 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Ly-63, TNFRSF9, ILA
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Format Conjugated
Clone 17B5
Host Species Golden Syrian Hamster
Isotype IgG
Antigen CD137 (4-1BB)
Concentration 0.2mg/mL
Species Reactivity Mouse
Applications Flow Cytometry
Quantity 25μg
Conjugate eFluor 450
Monoclonal or Polyclonal Monoclonal

The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays.