CD134 (OX40) Rat anti-Mouse, Clone: OX-86, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1341-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15297207

Quantity Price
1 £ 54.42 / 50µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Species Reactivity Mouse
Conjugate Unlabeled
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Western Blotting
Isotype IgG1
Quantity 50μg
Clone OX-86
Gene Alias Ly-70, TNFRSF4
Host Species Rat
Primary or Secondary Primary
Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Format Purified
Antigen CD134 (OX40)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.

The OX-86 monoclonal antibody reacts with mouse CD134, also known as OX40. A member of the TNF receptor superfamily, CD134 is a 50kDa type I membrane glycoprotein expressed by activated mouse T lymphocytes. Rat CD134 was initially identified as an activation marker only on activated CD4+ T cells. In contrast, mouse CD134 is expressed by both activated CD4+ and CD8+ T cells. The interaction of CD134 with CD252 (OX40 ligand) has been implicated in T cell-dependent humoral responses, regulation of primary T cell expansion, survival of T cells, size of the memory T cell pool, and regulation of tolerance in the CD4+ T cell compartment.