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CD133 (Prominin-1), PE, clone: TMP4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1338-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15506886

  • £195.81 / 100 tests


EU Stock 5
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Description

Description

Description: The TMP4 monoclonal antibody reacts with human CD133 (Prominin-1), a 120kDa member of the pentaspan family of proteins, which also includes Prominin-2. Their expression is found within plasma membrane protrusions such as epithelial microvilli. CD133 can exist in a number of alternatively spliced isoforms, and the protein has several N-linked glycosylation sites: the occurrence of both may be tissue-dependent. Human CD133 was first identified as an epitope expressed on CD34+ hematopoietic progenitors. Although the ligand and function of CD133 remain unknown, it has since proven to be very useful as a marker for both stem cells and cancer stem cells. In addition to its expression on hematopoietic precursors, CD133 has been used to identify tumorigenic colon cancer stem cells, brain cancer stem cells, prostate cancer stem cells, in addition to others.The binding of the TMP4 antibody does not block the binding of another anti-human CD133 antibody, EMK08 (cat. 12-1339) indicating that they recognize distinct epitopes.Applications Reported: This TMP4 antibody has been reported for use in flow cytometric analysis.Applications Tested: This TMP4 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD133
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
O43490
AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
TMP4
PE
PROM1
Conjugated
PROM1
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
8842
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