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CD131 Mouse anti-Human, PE, Clone: 1C1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1319-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15566876

  • £73.00 / 25 tests

Estimated Shipment date
from Supplier 28-02-2020

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Description

Description

The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common beta subunit. The a subunits are low affinity ligand binding proteins while the beta subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct beta subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine beta-subunits are 91% homologous at the amino acid level but only 56% homologous to the human beta subunit. Although neither the murine nor the human beta subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Specifications

Specifications

CD131
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P32927
IL-3 Receptor beta, IL-3 RB, Cytokine receptor common subunit beta, GM-CSF IL-3 IL-5 receptor common beta subunit, CD antigen CD131, CSF2RB, Csf2rb, Aic2b, Csf2rb1, Il3rb1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
1C1
PE
CSF2RB
Liquid
CSF2RB
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1439
Videos
Documents

For Research Use Only.