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CD127 Rat anti-Mouse, Clone: A7R34, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1271-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15287197

  • £225.61 / 500µg


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Disclaimers:

For Research Use Only.


Description

Description

The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity alpha subunit of the mouse IL-7 receptor. IL-7 receptor alpha chain is expressed by immature B cells in the bone marrow, double-negative (CD4-CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127.
Specifications

Specifications

CD127
A7R34
Unlabeled
Purified
Rat
500μg
Store at 2-8°C.
Monoclonal
Immunoprecipitation
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-7 Receptor alpha
IgG2a
RUO
Primary
Murine