missing translation for 'onlineSavingsMsg'
Learn More

CD126 Rat anti-Mouse, PE-Cy7, Clone: D7715A7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-1261-82

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15598466

  • £213.39 / 100µg


Estimated Shipment date
from Supplier 25-08-2017
Add to basket

Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody D7715A7 recognizes mouse CD126, the IL-6 receptor α chain, a member of the Ig superfamily. CD126 can heterodimerize with CD130 (gp130) to form the high affinity IL-6 receptor. Once IL-6 is bound, signaling from the CD130 subunit is initiated and the receptor complex is internalized. The IL-6 receptor is also reported to exist as a soluble version, which bound to IL-6 acts in trans to signal. Expression is found on T lymphocytes in the periphery and during development in the thymus is restricted to SP populations, unlike gp130 which is expressed in all thymocytes. Additional expression has been shown on activated B lymphocytes, macrophages, granulocytes and CD34+ hematopoietic progenitor cells. The monoclonal antibody D7715A7 binding can be blocked addition of ligand (IL-6).
Description & Specifications

Specifications

CD126
D7715A7
PE-Cy7
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-6 Receptor alpha
IgG2b
RUO
Primary
Murine