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CD126 Mouse anti-Human, PerCP-eFluor™ 710, Clone: 47.7G7.1F2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-1269-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15589176

  • £81.75 / 25 tests

Estimated Shipment
04-11-2020

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Description

Description

PerCP-eFluor® 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5. We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative. Please make sure that your instrument is capable of detecting this fluorochrome. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Specifications

Specifications

CD126
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P08887
CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991, IL6R
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
47.7G7.1F2
PerCP-eFluor™ 710
IL6R
Liquid
IL6R
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3570
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